23 April 1996 Osteointegration of KrF laser diamondlike carbon films deposited on Ti6Al4V alloy
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Abstract
The aim of present study was to experimentally evaluate osteointegration of the KrF laser diamond-like carbon coated titanium alloy Ti6Al4V cylindrical implants in a preliminary study in vivo. The films were created on cylindrical titanium substrates. Substrates were heated to 70 degree(s)C or 100 degree(s)C by resistively heated holder positioned 17 mm from sample. Target substrate distance was 5 cm, energy density of KrF laser beam on the target was 15 Jcm-2. Deposition chamber was evacuated to 10-2 Pa. Film various thickness were created. Control group contained the two samples of Ti6Al4V and two samples from sapphire. Ten rats Wistar were used in this investigation. The cylindrical implants were placed horizontally into the host bone. The position of implant in femur was controlled with radiograph. The implants were retrieved for 6 weeks. 70-nm thick sections (from 2 to 4 sections from each implant) were cut. The section were viewed using a polarized light photomicroscope Nikon. The percentage of bone/implant contact were determined. The level of osteointegration of the host bone were observed. The bone-implant femur and control femur were measured. Total or partial osteointegration was seen and measured depending on deposition conditions.
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Tatjana Dostalova, Miroslav Jelinek, Lucia Himmlova, "Osteointegration of KrF laser diamondlike carbon films deposited on Ti6Al4V alloy", Proc. SPIE 2672, Lasers in Dentistry II, (23 April 1996); doi: 10.1117/12.238762; https://doi.org/10.1117/12.238762
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