Subthreshold functional additivity occurring at the transition zone between temporary and permanent laser-induced visual loss

David O. Robbins; Harry Zwick

doi:10.1117/12.237517

1 April 1996 Subthreshold functional additivity occurring at the transition zone between temporary and permanent laser-induced visual loss

David O. Robbins, Harry Zwick

Author Affiliations +

Proceedings Volume 2674, Laser-Inflicted Eye Injuries: Epidemiology, Prevention, and Treatment; (1996) https://doi.org/10.1117/12.237517
Event: Photonics West '96, 1996, San Jose, CA, United States

Abstract

Damage criteria from laser irradiation have relied on fundoscopic and/or histological evidence. These methodologies have provided limited information regarding the functional impact of any observed damage and more importantly, do not lend themselves to assessments of the transition zone between temporary and permanent effects. Using a behavioral techniques, we have explored this transition zone with CW and Q-switched lasers. Our results demonstrate that daily exposure within the power levels of the transition zone become additive resulting in longer recovery times for successive exposures at the same power levels. Below this zone the impact of daily exposures appears non-additive; i.e., baseline acuity recovers to pre-exposure levels and both the magnitudes and durations of the recoveries appear unaffected by previous exposures. The additivity of successive exposures at the transition zone was most easily observed when relatively large-diameter (> 100 (mu) ), prolonged CW (100 msec) retinal exposures were made. When relatively small diameter (< 50 (mu) ), Q-switched (15 nsec) exposures were presented, significant decrements in acuity were not easily detected even with relatively intense exposures presented as single or multiple pulses within or across test sessions. These findings may reflect the contributions of different damage mechanisms evident in the transition zone.

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David O. Robbins and Harry Zwick "Subthreshold functional additivity occurring at the transition zone between temporary and permanent laser-induced visual loss", Proc. SPIE 2674, Laser-Inflicted Eye Injuries: Epidemiology, Prevention, and Treatment, (1 April 1996); https://doi.org/10.1117/12.237517

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