24 April 1996 Optical tomography of rat brain
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An experimental set-up for the optical tomography using photon density waves is described. The intensity of a NIR laser diode (825 nm) is modulated with a frequency of 110 MHz (modulating degree equal to 80%). The line scan of a rat brain at 64 linear steps and 64 angular steps contains the ac attenuation and the phase shift separately. Due to the impact of scattering in the medium these data are not the basis for a backprojection and deconvolution for the tomographic reconstruction itself. The first approach for a preprocessing consists in the determination of the geometry dependent modulation transfer function (MTF). The line scan is then corrected by the filter which varies with the position. An optical tomogram of a rat brain is presented. This procedure is suitable for biological objects up to a diameter of 30 mm approximately, for example small finger joints.
© (1996) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Juergen Beuthan, Juergen Beuthan, Richard Freyer, Richard Freyer, Olaf Minet, Olaf Minet, Cuong Tran Luu, Cuong Tran Luu, Uwe Hampel, Uwe Hampel, Rolf-Dieter Naber, Rolf-Dieter Naber, Gerhard J. Mueller, Gerhard J. Mueller, "Optical tomography of rat brain", Proc. SPIE 2676, Biomedical Sensing, Imaging, and Tracking Technologies I, (24 April 1996); doi: 10.1117/12.238823; https://doi.org/10.1117/12.238823

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