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24 April 1996 Quantitative analysis of coherent detection in a turbid medium
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Coherent detection is a promising technique for medical imaging, because it offers high spectral and temporal resolution, high spatial and angular resolution, and higher signal-to- noise ratio than direct detection. Analysis techniques developed for coherent lidars used in remote sensing of clouds are applicable to coherent medical imaging. Single-scattering models, in which analysis is normally performed using the irradiance of the transmitter and of the 'back-propagated local oscillator' (BPLO), have been used for a variety of beam profiles, but are not applicable to medical imaging in highly-scattering tissue. However, recent work has extended the BPLO technique to model lidar returns from dense, highly-scattering clouds. The computation is based on fluence rates determined using a Monte-Carlo model. Results are equally applicable to various coherent imaging systems, as well as vibration measurement, and holography. The equations are described and sample results are presented for reflection from tissue and transillumination. Variations in signal behavior with different layered structures in the tissue are considered.
© (1996) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Charles A. DiMarzio and Scott C. Lindberg "Quantitative analysis of coherent detection in a turbid medium", Proc. SPIE 2676, Biomedical Sensing, Imaging, and Tracking Technologies I, (24 April 1996);

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