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10 May 1996In-situ and in-vivo diagnostics of biological fluids
The ability of reliable, non-invasive, and quantitative characterization of biological fluids containing submicroscopic particles in a in-situ/in-vivo environment may open new possibilities to better understand these fluids. This paper focuses the use of a newly developed dynamic light scattering fiber optic probe to assist in this goal. A in-situ/on-line application to study protein aggregation and growth of protein crystals from solutions and one in-vivo application involving study of cataractogenesis in an animal model are presented.
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Rafat R. Ansari, Kwang I. Suh, "In-situ and in-vivo diagnostics of biological fluids," Proc. SPIE 2678, Optical Diagnostics of Living Cells and Biofluids, (10 May 1996); https://doi.org/10.1117/12.239532