11 April 1996 Fluorescent x-ray computed tomography with synchrotron radiation using fan collimator
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Abstract
We describe a new system of fluorescent x-ray computed tomography applied to image nonradioactive contrast materials in vivo. The system operates on the basis of computed tomography (CT) of the first generation. The experiment was also simulated using the Monte Carlo method. The research was carried out at the BLNE-5A bending-magnet beam line of the Tristan Accumulation Ring in Kek, Japan. An acrylic cylindrical phantom containing five paraxial channels of 5 and 4 mm diameters was imaged. The channels were filled with a diluted iodine-based contrast material, with iodine concentrations of 2 mg/ml and 500 (mu) g/ml. Spectra obtained with the system's high purity germanium (HPGe) detector separated clearly the K(alpha ) and K(beta 1) x-ray fluorescent lines, and the Compton scattering. CT images were reconstructed from projections generated by integrating the counts in these spectral lines. The method had adequate sensitivity and detection power, as shown by the experiment and predicted by the simulations, to show the iodine content of the phantom channels, which corresponded to 1 and 4 (mu) g iodine content per pixel in the reconstructed images.
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Tohoru Takeda, Masahiro Akiba, Tetsuya Yuasa, Masahiro Kazama, Atsunori Hoshino, Yuuki Watanabe, Kazuyuki Hyodo, F. Avraham Dilmanian, Takao Akatsuka, Yuji Itai, "Fluorescent x-ray computed tomography with synchrotron radiation using fan collimator", Proc. SPIE 2708, Medical Imaging 1996: Physics of Medical Imaging, (11 April 1996); doi: 10.1117/12.237832; https://doi.org/10.1117/12.237832
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