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16 April 1996 Application of 3D registration for detecting lesions in magnetic resonance breast scans
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In this paper we present 3D registration techniques for detecting breast cancer lesions based on differences between the high spatial resolution 'pre' and 'post' contrast administration MR breast scans. We also present registration techniques for detecting lesions based on the time course of enhancement after administration of the contrast agent based on changes in the low spatial resolution, high temporal resolution, dynamic MR data taken during the absorption of the contrast agent. Alignment of the 'pre' and 'post' MR data and of the dynamic MR images is done by a direct optimization technique to estimate a global affine deformation model using a coarse-to-fine control strategy over a 3D pyramid. This global model is followed by a one iteration flow estimation to account for any local non-rigidity. We present results of the registration process and visualization of the difference volumes obtained after alignment.
© (1996) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Rakesh Kumar, J. Charles Asmuth, Keith Hanna, James R. Bergen, C. Hulka, Daniel B. Kopans, R. Weisskoff, and Richard H. Moore "Application of 3D registration for detecting lesions in magnetic resonance breast scans", Proc. SPIE 2710, Medical Imaging 1996: Image Processing, (16 April 1996);

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