9 February 1996 Nanospace interface for the electrochemical communication between redox-active biomolecules and metal oxide electrodes
Author Affiliations +
Abstract
Oriented assembly and interfacial electron transfer of flavin coenzymes on titanium dioxide (TiO2) electrodes have been studied to develop the smart enzyme sensors or reactors. It was demonstrated that FMN and FAD were chemically adsorbed via phosphate moiety on TiO2 surface in weak acidic solutions to make monolayers. Quasi reversible slow electron transfer was observed on the FMN or FAD-adsorbed TiO2 electrodes. It was further demonstrated that the FMN-assembled TiO2 electrode electrochemically catalyzed the oxidation of NADH. The FMN-assembled TiO2 was then combined with some dehydrogenases and NADH to perform amperometric sensing for enzyme substrates. The results suggest that the assembled flavin coenzyme might be promising for a nanospace interface to achieve electrochemical communication between redox active biomolecules and the metal oxide electrodes.
© (1996) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Hiroaki Shinohara, "Nanospace interface for the electrochemical communication between redox-active biomolecules and metal oxide electrodes", Proc. SPIE 2716, Smart Structures and Materials 1996: Smart Materials Technologies and Biomimetics, (9 February 1996); doi: 10.1117/12.232138; https://doi.org/10.1117/12.232138
PROCEEDINGS
6 PAGES


SHARE
Back to Top