Photodynamic therapy of spread-skin malignancies with scanning electron beam-pumped semiconductor laser

Elena G. Vakoulovskaya M.D.; Gennadii A. Meerovich; Victor V. Shental M.D.; V. N. Ulasyuk

doi:10.1117/12.229489

8 January 1996 Photodynamic therapy of spread-skin malignancies with scanning electron beam-pumped semiconductor laser

Elena G. Vakoulovskaya M.D., Gennadii A. Meerovich, Victor V. Shental M.D., V. N. Ulasyuk

Proceedings Volume 2728, CIS Selected Papers: Laser Use in Oncology; (1996) https://doi.org/10.1117/12.229489
Event: CIS Selected Papers: Laser Use in Oncology, 1995, -, Russian Federation

Abstract

Photodynamic therapy (PDT) using quantoscope (scanning electron-beam pumped semiconductor laser, (lambda) equals 670 +/- 2 nm, P equals 10 W) and Phthalocyanine Al as photosensitizer (PS) have been provided in nine patients (27 tumor sites) with spread skin malignancies (basal cell, squamous cell cancer, melanoma, metastases of breast cancer) and cancer of lip T1 - T2 N0 M0. During PDT power density has been from 200 to 450 mW/cm², light doses ranging from 150 to 700 J/cm². We have fulfilled diagnostic of tumor after injection of PS and have controlled treatment using Spectral-Fluorescent Video Complex. In five patients (23 sites) we had complete clinical response and in four patients (4 sites) partial response after PDT. Results of our study show that using of scanning electron- beam pumped semiconductor laser is perspective in treating of spread skin malignancies.

Citation Download Citation

Elena G. Vakoulovskaya M.D., Gennadii A. Meerovich, Victor V. Shental M.D., and V. N. Ulasyuk "Photodynamic therapy of spread-skin malignancies with scanning electron beam-pumped semiconductor laser", Proc. SPIE 2728, CIS Selected Papers: Laser Use in Oncology, (8 January 1996); https://doi.org/10.1117/12.229489

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