Optimization approach to 3D reconstruction from solution x-ray scattering data

Yibin Zheng; Peter C. Doerschuk

doi:10.1117/12.255076

25 October 1996 Optimization approach to 3D reconstruction from solution x-ray scattering data

Yibin Zheng, Peter C. Doerschuk

Proceedings Volume 2827, Digital Image Recovery and Synthesis III; (1996) https://doi.org/10.1117/12.255076
Event: SPIE's 1996 International Symposium on Optical Science, Engineering, and Instrumentation, 1996, Denver, CO, United States

Abstract

Three methods for reconstructing icosahedrally-symmetric particles from solution x-ray scattering data are described. Such data is the spherical average of the magnitude-squared of the Fourier transform of the electron density in the particle and therefore is only one dimensional. Because of the limited amount of data, a priori information about the particle is crucial and the three methods differ in the description of the particle that is used. This type of reconstruction problem is important in the structural biology of spherical viruses, and example reconstructions from one such virus are described.

Citation Download Citation

Yibin Zheng and Peter C. Doerschuk "Optimization approach to 3D reconstruction from solution x-ray scattering data", Proc. SPIE 2827, Digital Image Recovery and Synthesis III, (25 October 1996); https://doi.org/10.1117/12.255076

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