In Japan the boron neutron capture therapy has been applied to more than 200 patients, mostly brain tumors and some melanomas. For brain tumors, Kyoto University, Kyoto Prefectural University of Medicine, Tsukuba University and National Kagawa Children's Hospital accept patients, and for melanomas, Kobe University and Mishima Institute of Dermatological Research accept patients so far. Recently the heavy water facility of Kyoto University Reactor has been upgraded for epithermal neutron as well as thermal neutron irradiations, and for the patient treatment during the continuous operation of the KUR.
Keiji Kanda, Keiji Kanda,
"Experience of boron neutron capture therapy in Japan", Proc. SPIE 2867, International Conference Neutrons in Research and Industry, (27 February 1997); doi: 10.1117/12.267900; https://doi.org/10.1117/12.267900