23 September 1996 Photodynamic therapy of recurrent cancer of oral cavity
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Abstract
Photo dynamic therapy (PDT) with use of two Russian photosensitizers, photohem (hematoporphyrine derivative) in the dosage 1.5-5.0 mg/kg of body weight and photosense in the dosage 0.5-1.5 mg/kg of body weight has been provided in 26 patients with spread recurrent tumors of oral cavity. During PDT power density has been from 50 to 1000 mW/cm2. Light irradiation doses ranging from 50 to 600 J/cm2. Therapeutic effect in term from 2 months to 3 years took place in 24 patients. In 18 cases complete resorption of tumor was achieved, in 6 cases, partial resorption. No effect was found in 2 cases. Our experience supposes that PDT appears to be a reasonable alternative to the traditional therapy of recurrent tumors of oral cavity.
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Eugeny Ph. Stranadko, Eugeny Ph. Stranadko, Oleg K. Skobelkin, Oleg K. Skobelkin, Nikolai A. Markichev, Nikolai A. Markichev, Michail V. Riabov, Michail V. Riabov, } "Photodynamic therapy of recurrent cancer of oral cavity", Proc. SPIE 2887, Lasers in Medicine and Dentistry: Diagnostics and Treatment, (23 September 1996); doi: 10.1117/12.251934; https://doi.org/10.1117/12.251934
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