5 December 1996 Radical formation during laser-tissue interaction
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Laser spectroscopic methods have been used for on-line investigations of laser tissue interaction processes concerning the production of toxic and carcinogenic substances in the laser plume during cutting and evaporation of tissue in laser surgery. Laser spectroscopic investigations demonstrated that the original tissue molecules were split into basic metastable compounds under the high temperature conditions in the reaction zone. The produced radicals are one source for the formation of the chemical s produced during the laser tissue interaction process. The formation of the harmful substances can be influenced by the surrounding gas atmosphere. These substances can be reduced significantly by the addition of an oxygen donor e.g. water, into the reaction zone.
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Juergen Lademann, Hans-Juergen Weigmann, H. Meffert, and Wolfram Sterry "Radical formation during laser-tissue interaction", Proc. SPIE 2923, Laser-Tissue Interaction and Tissue Optics II, (5 December 1996); doi: 10.1117/12.260736; https://doi.org/10.1117/12.260736

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