Kinetics of self-sensitized oxidation of dye for photodynamic therapy and of sensitized protein oxidation in aqueous solutions

Boris Ya. Kogan; Alexander V. Butenin; Oleg L. Kaliya; Eugeny A. Lukyanets

doi:10.1117/12.260787

4 December 1996 Kinetics of self-sensitized oxidation of dye for photodynamic therapy and of sensitized protein oxidation in aqueous solutions

Boris Ya. Kogan, Alexander V. Butenin, Oleg L. Kaliya, Eugeny A. Lukyanets

Author Affiliations +

Proceedings Volume 2924, Photochemotherapy: Photodynamic Therapy and Other Modalities II; (1996) https://doi.org/10.1117/12.260787
Event: BiOS Europe '96, 1996, Vienna, Austria

Abstract

The kinetics of oxygen consumption in aqueous solutions of sulphonated hydroxyaluminum phthalocyanine and protein under irradiation with He-Ne laser was studied using the method of sensitizer fluorescence saturation. The constants of triplet state quenching were determined. The dye is oxidized with superoxide anion-radical, whereas the protein -- mainly by singlet oxygen.

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Boris Ya. Kogan, Alexander V. Butenin, Oleg L. Kaliya, and Eugeny A. Lukyanets "Kinetics of self-sensitized oxidation of dye for photodynamic therapy and of sensitized protein oxidation in aqueous solutions", Proc. SPIE 2924, Photochemotherapy: Photodynamic Therapy and Other Modalities II, (4 December 1996); https://doi.org/10.1117/12.260787

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