6 December 1996 Quantification of hemoglobin saturation on tissue phantom using phase-modulation spectroscopy
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Abstract
Int his article, we analytically present the influence of the systematic error due to the theoretical assumptions on the blood oxygenation determination using a 'phase-only' dual-wavelength phase-modulation spectroscopy (PMS). To approach an accurate quantification of hemoglobin saturation, an empirical method to experimentally acquire the initial phase-shift value in oxygenation quantification form PMS data is investigated on blood-perfused phantom. Our results show that the quantification error of blood oxygenation determination can be substantially compensated by using the acquired (theta) 0(lambda ) method and is confirmed to be less than 10 percent by comparison with the measured results of the Pt electrode.
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Congwu Du, Congwu Du, Hanli Liu, Hanli Liu, Britton Chance, Britton Chance, "Quantification of hemoglobin saturation on tissue phantom using phase-modulation spectroscopy", Proc. SPIE 2925, Photon Propagation in Tissues II, (6 December 1996); doi: 10.1117/12.260836; https://doi.org/10.1117/12.260836
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