Detection of cervical precancer using optical spectroscopy (Extended Abstract)

Nirmala Ramanujam; Michele Follen-Mitchell; Anita Mahadevan-Jansen; Constantinos Pitris; Anant Agrawal; Sharon L. Thomsen M.D.; Gregg Staerkel; Thomas C. Wright Jr.; Rebecca R. Richards-Kortum

doi:10.1117/12.260814

6 December 1996 Detection of cervical precancer using optical spectroscopy (Extended Abstract)

Nirmala Ramanujam, Michele Follen-Mitchell, Anita Mahadevan-Jansen, Constantinos Pitris, Anant Agrawal, Sharon L. Thomsen M.D., Gregg Staerkel, Thomas C. Wright Jr., Rebecca R. Richards-Kortum

Author Affiliations +

Proceedings Volume 2926, Optical Biopsies and Microscopic Techniques; (1996) https://doi.org/10.1117/12.260814
Event: BiOS Europe '96, 1996, Vienna, Austria

Abstract

The continuing morbidity and mortality rate related to cervical cancer necessitates an improvement in current screening and diagnostic programs that target early detection of its curable precursor, cervical squamous intraepithelial lesion (SIL). Optical spectroscopy is a technique that has the capability to improve the accuracy and efficacy of current techniques for the detection of SILs. We have utilized fluorescence spectroscopy for the differential detection of SILs, in vivo and we have also evaluated the utility of near infrared (IR) Raman spectroscopy for the characterization of SILs in vitro.

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Nirmala Ramanujam, Michele Follen-Mitchell, Anita Mahadevan-Jansen, Constantinos Pitris, Anant Agrawal, Sharon L. Thomsen M.D., Gregg Staerkel, Thomas C. Wright Jr., and Rebecca R. Richards-Kortum "Detection of cervical precancer using optical spectroscopy (Extended Abstract)", Proc. SPIE 2926, Optical Biopsies and Microscopic Techniques, (6 December 1996); https://doi.org/10.1117/12.260814

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KEYWORDS

Algorithm development

Raman spectroscopy

Tissues

Luminescence

Optical spectroscopy

Diagnostics

Fluorescence spectroscopy

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