Diagnostics of cancer by fiber optic evanescent wave FTIR (FEW-FTIR) spectroscopy

Natalia I. Afanasyeva; Sergei F. Kolyakov; Vladilen S. Letokhov; Victor V. Sokolov; George A. Frank

doi:10.1117/12.259954

26 November 1996 Diagnostics of cancer by fiber optic evanescent wave FTIR (FEW-FTIR) spectroscopy

Natalia I. Afanasyeva, Sergei F. Kolyakov, Vladilen S. Letokhov, Victor V. Sokolov, George A. Frank

Proceedings Volume 2928, Biomedical Systems and Technologies; (1996) https://doi.org/10.1117/12.259954
Event: BiOS Europe '96, 1996, Vienna, Austria

Abstract

The fiberoptic evanescent wave Fourier transform IR spectroscopy (FEWS) using fiberoptic sensors operated in the attenuated total reflection (ATR) regime in the mid-IR region of the spectrum (4 to 16 micrometer) has recently found application in the diagnostics of biotissues. The silver halide fibers used are non-toxic, non-hygroscopic, flexible and soft and are characterized by a low optical loss. The method allows for non-invasive and rapid (seconds) direct measurements of the spectra of normal and pathological tissues in vitro, ex vivo and in vivo with the aim of express testing of various tumor tissues at the early stages of their development. The method is expected to be further developed for endoscopic and biopsy applications.

Citation Download Citation

Natalia I. Afanasyeva, Sergei F. Kolyakov, Vladilen S. Letokhov, Victor V. Sokolov, and George A. Frank "Diagnostics of cancer by fiber optic evanescent wave FTIR (FEW-FTIR) spectroscopy", Proc. SPIE 2928, Biomedical Systems and Technologies, (26 November 1996); https://doi.org/10.1117/12.259954

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