25 November 1996 Different sensitivity of cells from tumor-bearing organisms to continuous-wave and pulsed laser radiation (lambda = 632.8 nm) evaluated by chemiluminescence test
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Abstract
Chemiluminescence test results were used to evaluate the sensitivity of human blood and murine splenocytes to continuous-wave (CW) and pulsed He-Ne laser light. It is demonstrated that CW radiation has in our experimental conditions practically no effect on the luminol-amplified chemiluminescence of four models under study. The pulsed radiation had a week inhibiting effect on the samples from healthy organisms but inhibited markedly the chemiluminescence of samples from tumor-bearing organisms. The effect depended on duration of dark period between pulses. A transient local heating mechanism is proposed to explain the inhibition of activity of NADPH-oxidase.
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Tiina I. Karu, T. P. Ryabykh, Sergei N. Antonov, Vladilen S. Letokhov, "Different sensitivity of cells from tumor-bearing organisms to continuous-wave and pulsed laser radiation (lambda = 632.8 nm) evaluated by chemiluminescence test", Proc. SPIE 2929, Effects of Low-Power Light on Biological Systems II, (25 November 1996); doi: 10.1117/12.259981; https://doi.org/10.1117/12.259981
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