8 November 1996 Laser damage of skin by 1540-nm Er-glass laser radiation: impact on laser safety standards
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Proceedings Volume 2965, ALT '96 International Symposium on Laser Methods for Biomedical Applications; (1996); doi: 10.1117/12.257379
Event: ALT '96 International Symposium: Laser Methods for Biomedical Applications, 1996, Heraklion, Crete, Greece
Abstract
The skin response was studied for different radiant exposure of short and long laser pulses and reaction to multipulse action using Er-glass laser radiation. Lesion ranging from a mild erythema to tissue coagulation were produced on porcine skin. Radiant exposure producing 50 percent probability of a particular grade of lesion were established. A dependence of ED50 of minimum erythema versus number of pulses and beam cross section were studied. The dose-response relationship for producing different grades of burns were determined for energy densities of single laser pulse within the range 0.5- 35 J/cm2 and pulse duration 100 ns and 3 ms. The single pulse dose in a chain of repetitive pluses producing minimum erythema were determined for 2n(n equals 1-6 pulses). The minimum reaction of skin on laser irradiance were studied for different beam diameter. The reaction of skin is mostly considered as local super heating. The data obtained are adequate to update safety standards for cutaneous injury within thee ranges of radiant exposure and beam spotsize.
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Alexei V. Lukashev, Boris I. Denker, Pavel P. Pashinin, Sergey E. Sverchkov, "Laser damage of skin by 1540-nm Er-glass laser radiation: impact on laser safety standards", Proc. SPIE 2965, ALT '96 International Symposium on Laser Methods for Biomedical Applications, (8 November 1996); doi: 10.1117/12.257379; https://doi.org/10.1117/12.257379
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KEYWORDS
Skin

Pulsed laser operation

Standards development

Laser safety

Q switching

Laser energy

Glasses

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