External standard for measurements with the Scheimpflug slitlamp microscope

Per G. Soederberg; Wen Qian; Enping Chen; Mats Johansson

doi:10.1117/12.275103

26 May 1997 External standard for measurements with the Scheimpflug slitlamp microscope

Per G. Soederberg, Wen Qian, Enping Chen, Mats Johansson

Proceedings Volume 2971, Ophthalmic Technologies VII; (1997) https://doi.org/10.1117/12.275103
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

Scheimpflug slitlamp microscopy is the outstanding method to record nuclear light scattering from the crystalline lens. Until yet, calibration of measurements with this device has not been possible. In the current work, an external standard for Scheimpflug slitlamp microscopy has been developed. The standard makes it possible to calibrate measurements within a research center and between research centers. The standard consists of an artificial anterior eye chamber that is filled with an aqueous solution of polystyrene spheres. The standard is placed at a position corresponding to a measured eye in the Scheimpflug slitlamp camera. A recording is taken. The higher the concentration of the scatterer, the more light scattering is recorded. A calibration curve relating concentration of light scatterer in the phantom to units of internal gray scale in the Scheimpflug microscope, is created. The scattering of a patient lens is recorded in units of internal gray scale and transformed to concentration of standard scatterer. The developed external standard opens the possibility to make comparative measurements of nuclear lens scattering in cataract for anti cataract drug development and cataract epidemiology studies.

Citation Download Citation

Per G. Soederberg, Wen Qian, Enping Chen, and Mats Johansson "External standard for measurements with the Scheimpflug slitlamp microscope", Proc. SPIE 2971, Ophthalmic Technologies VII, (26 May 1997); https://doi.org/10.1117/12.275103

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