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8 May 1997 Next-generation light delivery system for multitreatment extended-duration photodynamic therapy (MED-PDT)
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Abstract
The primary focus of laser based oncologic PDT has been on the treatment of skin and hollow organ tumors. Extending PDT to other primary internal lesions and metastasis requires a different approach. Light Sciences has developed a series of semiconductor-based devices which will be completely implanted in the patient using established, minimally invasive surgical techniques. These devices are energized noninvasively utilizing inductive coupling. The light delivery system will allow the clinician to modulate the intensity, spatial distribution, and duration of light delivery in order to maximize the benefits derived from each PDT drug dose. Light Sciences' technology minimizes patient risk and discomfort, is cost competitive, and expands the treatment options available to the clinician. Avoidance of lengthy operations, bone marrow suppression, and an emphasis on organ preservation allow this next generation of PDT light delivery devices to be effectively integrated with other forms of cancer treatment, if desired. We have termed our technique 'Multi-treatment Extended Duration PDT'. In what follows, we shall describe Light Sciences' technology and development of minimally invasive oncologic PDT.
© (1997) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
James C. Chen M.D. "Next-generation light delivery system for multitreatment extended-duration photodynamic therapy (MED-PDT)", Proc. SPIE 2972, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy VI, (8 May 1997); https://doi.org/10.1117/12.273501
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