Evaluation of vernier acuity near healed retinal laser lesions

Elmar T. Schmeisser

doi:10.1117/12.275232

2 May 1997 Evaluation of vernier acuity near healed retinal laser lesions

Elmar T. Schmeisser

Proceedings Volume 2974, Laser and Noncoherent Ocular Effects: Epidemiology, Prevention, and Treatment; (1997) https://doi.org/10.1117/12.275232
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

Seven Cynomolgus fasciculata who had graded laser lesions placed in own eye 6 years previously were evaluated for their vernier acuity by electrophysiologic recording techniques. In these experiments, 95 percent contrast vernier acuity targets were presented at high luminance levels to anesthetized primates. Visual evoked potentials were recorded by conventional means form scalp electrodes through hospital grade amplifiers. All animal testing was performed under IACUC approved protocols. The single q-switched pulses form a neodymium-YAG laser had produced lesions of 4 types: no visible change, minimal visible lesions, 'white dot' lesions and 'red dot' lesions in the eye at the time of placement. Single exposures had been made in four locations: 5 degrees superior, inferior and temporal to the fovea, and one foveally. Vernier recording proved somewhat successful in smaller animals with less than contained retinal hemorrhage lesions in the fovea. Initial analyses demonstrated a significant decrease of the pattern response signal/noise in the experimental eye overall, and an apparent relative loss of vernier signal in some lesioned eyes. Animals with the more severe lesions have somewhat degraded small patten responses and no recordable vernier response. Apparent lesser losses produced less effect.

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Elmar T. Schmeisser "Evaluation of vernier acuity near healed retinal laser lesions", Proc. SPIE 2974, Laser and Noncoherent Ocular Effects: Epidemiology, Prevention, and Treatment, (2 May 1997); https://doi.org/10.1117/12.275232

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KEYWORDS

Eye

Visualization

Statistical analysis

Signal attenuation

Retina

Electrodes

Signal to noise ratio

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