2 May 1997 Variation of retinal ED50 with exposure duration for near-IR sources
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A body of data relates the ED50 for laser-induced retinal damage to exposure duration for visible-wavelength laser exposure and for 1064 nm laser exposure. The database, extending from sub-nanosecond exposures to kilosecond exposures, can for the most part, be fit to models based on thermal interactions, thermal-mechanical mechanisms, and photochemical processes. Exceptions to this fit occur between 1 and 100 microseconds where the damage mechanism transitions from exclusively thermal to thermal-mechanical. Disagreement exists as to whether this anomalous dip of ED50 is real or is an artifact of the data. We determined the laser-induced retinal ED50 in Rhesus monkey eyes for several exposure durations from 12 nanoseconds to 1000 milliseconds at 755 nm using a dye laser, an alexandrite laser, and a Ti:Sapphire laser. These data do not show a dip in ED50 in the microsecond time period.
© (1997) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
David J. Lund, Daniel R. Fuller, Stephen W. Hoxie, P.R. Edsall, "Variation of retinal ED50 with exposure duration for near-IR sources", Proc. SPIE 2974, Laser and Noncoherent Ocular Effects: Epidemiology, Prevention, and Treatment, (2 May 1997); doi: 10.1117/12.275254; https://doi.org/10.1117/12.275254

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