Diode-laser ablation therapy for submucosal gastric cancer using indocyanine-green solution injection to the submucosa

Takuya Hayashi; Tsunenori Arai; Shigeki Tokonabe; Harumi Itoh; Makoto Kikuchi; Shoryoku Hino; Katsunori Masuda; Hiroaki Suzuki; Hisao Tajiri; Kunihiko Hino; Yashiroh Nogami

doi:10.1117/12.275505

16 June 1997 Diode-laser ablation therapy for submucosal gastric cancer using indocyanine-green solution injection to the submucosa

Takuya Hayashi, Tsunenori Arai, Shigeki Tokonabe, Harumi Itoh, Makoto Kikuchi, Shoryoku Hino, Katsunori Masuda, Hiroaki Suzuki, Hisao Tajiri, Kunihiko Hino, Yashiroh Nogami

Author Affiliations +

Proceedings Volume 2975, Laser-Tissue Interaction VIII; (1997) https://doi.org/10.1117/12.275505
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

A 805-nm diode laser ablation therapy with indocyanine green (ICG) was studied for the endoscopic treatment of early gastric cancer. The ICG solution with 1mg/ml was administrated to the submucosa of the resected porcine and anesthetized canine stomach for the purpose of enhancing the tissue absorption to the laser light. We established complete removal of the mucosa and the submucosa with laser power of 12 or 25 watts. The proper muscle was intact because the ICG solution prevents the laser light penetration to the proper muscle. An ablated depth could be easily recognized by observing the ablated surface color. Our results showed that the combination of the 805 nm diode laser irradiation and the submucosal injection of the ICG solution might provide selective and controllable endoscopic treatment for early gastric cancer.

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Takuya Hayashi, Tsunenori Arai, Shigeki Tokonabe, Harumi Itoh, Makoto Kikuchi, Shoryoku Hino, Katsunori Masuda, Hiroaki Suzuki, Hisao Tajiri, Kunihiko Hino, and Yashiroh Nogami "Diode-laser ablation therapy for submucosal gastric cancer using indocyanine-green solution injection to the submucosa", Proc. SPIE 2975, Laser-Tissue Interaction VIII, (16 June 1997); https://doi.org/10.1117/12.275505

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