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16 June 1997 Sol gel-based fiber optic pH sensor
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Proceedings Volume 2976, Biomedical Sensing, Imaging, and Tracking Technologies II; (1997)
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States
We report here on the development of a sol-gel based fiber optic sensor to monitor local blood pH. These sensors are being developed for invasive medical applications; that is, they will be coaxially threaded through a catheter beyond an occlusion in the vascular system. The fiber optic pH sensor design was based on the immobilization of a pH sensitive dye, seminaphthorhodamine-1 carboxylate, onto the tip or surface of an optical fiber using the sol-gel method. The fiber optic pH sensor was tested in phosphate buffer saline and human whole blood using a miniature fluorimeter system. Linear responses were obtained in blood in the pH range 6.7 to 8.0, which demonstrates potential for use for in vivo sensing.
© (1997) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Sheila A. Grant and Robert S. Glass "Sol gel-based fiber optic pH sensor", Proc. SPIE 2976, Biomedical Sensing, Imaging, and Tracking Technologies II, (16 June 1997);

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