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18 August 1997 Local diffuse reflectance from three-layered skin tissue structures
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We consider two different skin structure models. The first structure consists of epidermis, dermis/blood, and subcutaneous tissue. The second structure consists of epidermis/dermis, adipose tissue and muscle tissue. A new solution based on diffusion theory of the cw local diffuse reflectance from a three-layered skin tissue structure is presented. Comparisons with Monte Carlo simulations are carried out favorably. It is shown that the functional form of the radial dependence of the diffuse reflectance from multilayer and single layer models are identical. We use a modified expression originating from diffusion theory to fit the diffuse reflectance. We discuss the sensitivity of the local diffuse reflectance as a function of the optical properties of separate layers in both structures. Moreover, we investigate the influence on the local diffuse reflectance with changes in the optical properties corresponding to normal changes in tissue glucose concentration and blood volume. The necessity of multilayer models lies within their ability to provide a detailed description of the light-tissue interaction rate than their applicability to practical data analysis of the local diffuse reflectance measurements.
© (1997) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Peter E. Andersen, Jan Sorensen Dam, Paul Michael Petersen, and Peter Bjerring "Local diffuse reflectance from three-layered skin tissue structures", Proc. SPIE 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II, (18 August 1997);

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