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18 August 1997 Monitoring of cerebral hemodynamics during open-heart surgery in children using near-infrared intensity-modulated spectroscopy
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Abstract
Neurological impairments following cardiopulmonary bypass (CPB) during open heart surgery can result from microembolism and ischaemia. Here we present preliminary results from monitoring cerebral hemodynamics during CPB with near infrared intensity modulated spectroscopy. In particular, the study had two main objectives: (1) to monitor the oxy- and deoxy hemoglobin concentrations and their changes during the CPB surgery and (2) to monitor the transport scattering coefficient ((mu) s') of the brain especially during cooling and rewarming. A new method for the calculation of absolute absorption coefficients ((mu) a) was also tested. This method is based upon the monitoring of attenuation and phase changes that are induced by variations in absorption. These variations can be generated either by alterations in the tissue oxygenation or by injecting a dye (indocyanine green) into the CPB circuit. Absolute oxy- and deoxyhemoglobin concentrations and their changes during the CPB were calculated. The preliminary results suggest that cooling of the brain does not significantly alter (mu) s'.
© (1997) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Matthias Kohl-Bareis, Russell W. Watson, Gabriel Chow, Idris Roberts, David T. Delpy, and Mark Cope "Monitoring of cerebral hemodynamics during open-heart surgery in children using near-infrared intensity-modulated spectroscopy", Proc. SPIE 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II, (18 August 1997); https://doi.org/10.1117/12.280272
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