Problem of macroinhomogeneity detectability in optical tomography studies of strongly scattering media

Vladimir V. Lyubimov; Evgeny P. Mironov; Alexander G. Murzin; Vladimir B. Volkonski; Olga V. Kravtsenyuk

doi:10.1117/12.280216

18 August 1997 Problem of macroinhomogeneity detectability in optical tomography studies of strongly scattering media

Vladimir V. Lyubimov, Evgeny P. Mironov, Alexander G. Murzin, Vladimir B. Volkonski, Olga V. Kravtsenyuk

Proceedings Volume 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II; (1997) https://doi.org/10.1117/12.280216
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

In the diffusion equation approximation, the photon mean trajectory (PMT) and photon path deviation were calculated in relation to scattering medium optical characteristics and methods of measurements (time- or frequency-domain). It was shown that in macroinhomogeneity detection there exists an optimum combination between the spatial resolution (which is defined by photon path standard deviations from PMT) and the value of signal perturbation induced by inhomogeneities. One can evaluate this optimum by the scale matching of photon path rms deviations and macroinhomogeneity size. In turn, such a matching can be realized by the proper choice of the source and detector mutual positions and the values of temporal delay in time-domain or modulation frequency in frequency-domain measurements.

Citation Download Citation

Vladimir V. Lyubimov, Evgeny P. Mironov, Alexander G. Murzin, Vladimir B. Volkonski, and Olga V. Kravtsenyuk "Problem of macroinhomogeneity detectability in optical tomography studies of strongly scattering media", Proc. SPIE 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II, (18 August 1997); https://doi.org/10.1117/12.280216

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