Contact fiber optic sensor for endoscopic laser-induced fluorescence analysis

Nikolay A. Denisov; Sergiy M. Dets; Igor Kravchenko

doi:10.1117/12.273556

7 May 1997 Contact fiber optic sensor for endoscopic laser-induced fluorescence analysis

Nikolay A. Denisov, Sergiy M. Dets, Igor Kravchenko

Proceedings Volume 2980, Advances in Fluorescence Sensing Technology III; (1997) https://doi.org/10.1117/12.273556
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

During the clinical endoscopic LIF-diagnostics of human digestion organs is needed to register fluorescence spectra in situ. Taking into account intensive bloodstream and therefore strong hemoglobin absorption of laser light the registered fluorescence signal is strongly dependent on distal probe geometry. The contact optics sensor is specially designed to enhance acquisition of auto- and exogenous fluorescence spectra from tissues. The fiber optics sensor consists of cylindrical sapphire or silica body with flat proximal and spherical distal end and tapered tip. The latter one has been made of optical material. This tip has been arranged abutting against the proximal end of the cylindrical body. Such sensor design offers to collect autofluorescent light in wide angle region effectively. Moreover that offers to use sensor simultaneously as an efficient both laser radiation collector and fiber coupler to transport exciting light at the testing site and backward. The produced distal probe has been used through the biopsy channel to endoscope. Original beam splitter throws 80% of fluorescent signal toward detector and simultaneously transmits up to 85% of He-Cd laser radiation to the tissue.

Citation Download Citation

Nikolay A. Denisov, Sergiy M. Dets, and Igor Kravchenko "Contact fiber optic sensor for endoscopic laser-induced fluorescence analysis", Proc. SPIE 2980, Advances in Fluorescence Sensing Technology III, (7 May 1997); https://doi.org/10.1117/12.273556

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KEYWORDS

Luminescence

Tissues

Fiber optics sensors

Natural surfaces

Sensors

Endoscopy

Sapphire

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