22 May 1997 Digital signal processing in optical coherence tomography
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Optical coherence tomography (OCT) is a novel medical imaging modality which utilizes coherence ranging to perform high resolution (approximately 10 micrometer) non-invasive sub- surface imaging of biostructures. We have developed an OCT system consisting of a low-coherence interferometer and a calibration interferometer allowing sub-micron interferogram acquisition accuracy. We propose some digital signal processing strategies for image enhancement in optical coherence tomography. A linear shift invariant system model is presented for describing coherent light-tissue interactions in optical coherence tomography. In this model, the electric field backscattered from a target specimen is treated as a convolution of the incident field and a postulated tissue impulse response which describes the profile of scattering sites within the specimen. Based on this model, a novel technique for enhancing the sharpness of optical coherence tomographic images of biological structures using digital deconvolution is demonstrated. Using this approach, resolution improvement by a factor of greater than 2.2 is achieved in the longitudinal direction.
© (1997) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Manish D. Kulkarni, Joseph A. Izatt, "Digital signal processing in optical coherence tomography", Proc. SPIE 2981, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications, (22 May 1997); doi: 10.1117/12.274307; https://doi.org/10.1117/12.274307

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