Fluorescence lifetime imaging of the oxygen distribution in the skin

Dietmar Kieslinger; Sonja Draxler; Janusz Puzon; Max E. Lippitsch

doi:10.1117/12.273620

2 May 1997 Fluorescence lifetime imaging of the oxygen distribution in the skin

Dietmar Kieslinger, Sonja Draxler, Janusz Puzon, Max E. Lippitsch

Proceedings Volume 2982, Optical Diagnostics of Biological Fluids and Advanced Techniques in Analytical Cytology; (1997) https://doi.org/10.1117/12.273620
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

An instrument has been designed and implemented capable of mapping oxygen distribution in skin tissue over an area of several square centimeters with a spatial resolution of better than 1 mm and with a resolution in oxygen partial pressure of better than 5 torr. The measurement scheme is optical and is based on luminescence lifetime. It is non- invasive and avoids any patient contact with electrical parts. The instrument should be a valuable supplement to other clinical methods for monitoring microcirculation and peripheral oxygen supply.

Citation Download Citation

Dietmar Kieslinger, Sonja Draxler, Janusz Puzon, and Max E. Lippitsch "Fluorescence lifetime imaging of the oxygen distribution in the skin", Proc. SPIE 2982, Optical Diagnostics of Biological Fluids and Advanced Techniques in Analytical Cytology, (2 May 1997); https://doi.org/10.1117/12.273620

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