Synchrotron-based micro-CT of in-situ biological basic functional units and their integration

Erik Leo Ritman M.D.; Steven Mark Jorgensen; Patricia E. Beighley; Paul J. Thomas; John H. Dunsmuir; J. Carlos Romero; Russell T. Turner; Mark E. Bolander

doi:10.1117/12.279356

24 October 1997 Synchrotron-based micro-CT of in-situ biological basic functional units and their integration

Erik Leo Ritman M.D., Steven Mark Jorgensen, Patricia E. Beighley, Paul J. Thomas, John H. Dunsmuir, J. Carlos Romero, Russell T. Turner, Mark E. Bolander

Author Affiliations +

Proceedings Volume 3149, Developments in X-Ray Tomography; (1997) https://doi.org/10.1117/12.279356
Event: Optical Science, Engineering and Instrumentation '97, 1997, San Diego, CA, United States

Abstract

Use of synchrotron generated x-ray for micro-CT is particularly powerful for several reasons. These include the high x-ray flux which permits short duration exposure and hence scan durations, the narrow bandwidth of the x-ray energy which permits quantitative CT imaging with high accuracy of the measured attenuation coefficient and the fact that the x-ray photon energy can be adjusted allows element selective imaging. Another advantage is that the radiation is close to parallel so that the tomographic image reconstruction process is facilitated. On the other hand, synchrotron-based micro-CT imaging does have the limitation of a rather small field of view being illuminated. This means that specimens larger than the field of view also create problems for the conventional 'global' tomographic image reconstruction algorithms. Fortunately, recently developed 'local' reconstruction algorithms can, in large measure, overcome this limitation of the synchrotron generated x-ray field.

Citation Download Citation

Erik Leo Ritman M.D., Steven Mark Jorgensen, Patricia E. Beighley, Paul J. Thomas, John H. Dunsmuir, J. Carlos Romero, Russell T. Turner, and Mark E. Bolander "Synchrotron-based micro-CT of in-situ biological basic functional units and their integration", Proc. SPIE 3149, Developments in X-Ray Tomography, (24 October 1997); https://doi.org/10.1117/12.279356

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available