19 January 1998 Gd-DTPA-enhanced magnetic resonance imaging (MRI) for the follow-up of laser-induced thermotherapy (LITT): trial to determine a useful examination schedule
Author Affiliations +
Abstract
Purpose: To evaluate gadolinium-DTPA-enhanced MRI for follow-up monitoring of laser-induced thermotherapy (LITT) and to determine of a useful examination schedule. Materials and Methods: LITT Of the liver was performed in 55 rabbits using a Nd:YAG laser (4 w power output, 840 s exposure time). Gd-DTPA MRI and histological examinations were performed at different times (0 - 168 days). Results: Laser- induced lesions underwent regeneration and volume size reduction (69% after 168 days). The correlation coefficient (MR vs macroscopic analysis) for the mean lesion diameter was r equals 0.96. Histology of lesions comprised the four zones that correlated best with MRI findings. Coagulation necroses immediately after LITT were seen as an area of no enhancement on Gd-DTPA MRI. Circular enhancement was first seen 72 - 96 hours after LITT, which was due to early mesenchymal proliferation. Conclusions: Gd-DTPA MRI is a good monitoring procedure for LITT. MRI should be performed 24 and 96 hours after LITT.
© (1998) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Christoph-Thomas Germer, Christoph Martin Isbert, Dirk Albrecht, Joerg-Peter Ritz, Andreas Schilling, Andre Roggan, Karl Juergen Wolf, Gerhard J. Mueller, Heinz-Johannes Buhr, "Gd-DTPA-enhanced magnetic resonance imaging (MRI) for the follow-up of laser-induced thermotherapy (LITT): trial to determine a useful examination schedule", Proc. SPIE 3193, Photothermal Therapies in Medicine, (19 January 1998); doi: 10.1117/12.300826; https://doi.org/10.1117/12.300826
PROCEEDINGS
9 PAGES


SHARE
Back to Top