Open Access Paper
1 January 1998 In-vivo local determination of tissue optical properties
Frederic P. Bevilacqua, Dominique Piguet, Pierre Marquet, Jeffrey D. Gross, Bruce J. Tromberg, Christian D. Depeursinge
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Abstract
Local and superficial optical characterization of biological tissues can be achieved by measuring the spatially resolved diffuse reflectance at small source-detector separations. The sensitivity of the signal to the phase function, absorption and scattering coefficients were studied using Monte Carlo simulations. Measurements of spatially resolved reflectance were performed in vivo on human brain with source-detector separations from 0.3 to 1.5 mm. Distinct optical properties were found between normal cortex, astrocytoma of optic nerve and normal optic nerve.
© (1998) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Frederic P. Bevilacqua, Dominique Piguet, Pierre Marquet, Jeffrey D. Gross, Bruce J. Tromberg, and Christian D. Depeursinge "In-vivo local determination of tissue optical properties", Proc. SPIE 3194, Photon Propagation in Tissues III, (1 January 1998); https://doi.org/10.1117/12.301063
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Cited by 13 scholarly publications.
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KEYWORDS
In vivo imaging

Optical properties

Tissues

Optic nerve

Absorption

Biomedical optics

Diffuse reflectance spectroscopy

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