Monitoring of cerebral hemodynamics and oxygenation by continuous-wave optical spectroscopy during asphyxia in newborn piglets

Miljan R. Stankovic M.D.; Alan M. Fujii; Debra Kirby; David A. Boas; Vasilis Ntziachristos; Phillip G. Stubblefield

doi:10.1117/12.301040

1 January 1998 Monitoring of cerebral hemodynamics and oxygenation by continuous-wave optical spectroscopy during asphyxia in newborn piglets

Miljan R. Stankovic M.D., Alan M. Fujii, Debra Kirby, David A. Boas, Vasilis Ntziachristos, Phillip G. Stubblefield

Author Affiliations +

Proceedings Volume 3194, Photon Propagation in Tissues III; (1998) https://doi.org/10.1117/12.301040
Event: BiOS Europe '97, 1997, San Remo, Italy

Abstract

The present study demonstrated that optical variables HbT and SmcO₂ can be used to monitor changes in cerebral hemodynamics and oxygenation during asphyxia. Unfortunately none of the individual optical variables alone could be used to monitor changes in cerebral hemodynamics and oxygenation under a variety of possible clinical circumstances. However, all variables together, forming patterns unique to the commonly occurring physiological conditions, might potentially serve as a `silver standard' to aid interpretations of optical signals in clinical settings where `gold standard' techniques are not available, i.g. in the human fetus and neonate.

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Miljan R. Stankovic M.D., Alan M. Fujii, Debra Kirby, David A. Boas, Vasilis Ntziachristos, and Phillip G. Stubblefield "Monitoring of cerebral hemodynamics and oxygenation by continuous-wave optical spectroscopy during asphyxia in newborn piglets", Proc. SPIE 3194, Photon Propagation in Tissues III, (1 January 1998); https://doi.org/10.1117/12.301040

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