1 January 1998 Near-infrared spectroscopy of the human brain: effects of apnea and hypercapnia on the intensity and phase of backscattered light
Author Affiliations +
Abstract
The effects of hypercapnia on the intensity and phase of near infrared light back-scattered by the head were studied on eight healthy humans and two patients affected by monohemispheric lesions in the Middle Cerebral Artery (MCA) territory. A decrease in the light intensity and a variation of the phase were detected in all healthy subjects during apnea and hypercapnia. Only negligible changes were observed in the affected hemisphere of the patients. A concomitant study by Transcranial Doppler Sonography (TCD) showed an increase of the blood flow during hypercapnia both in normal hemispheres and, to a less extent, in the affected hemisphere of patients. This suggests that NIRS (Near Infrared Spectroscopy) is more sensitive to alterations of more cortical brain vascular system than TCD which is mainly testing MCA in the depth.
© (1998) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Nicola Rosato, Nicola Rosato, Fabrizio Vernieri, Fabrizio Vernieri, Francesco Tibuzzi, Francesco Tibuzzi, Francesco Passarelli, Francesco Passarelli, Alessandro Finazzi Agro, Alessandro Finazzi Agro, Paolo Maria Fasella, Paolo Maria Fasella, Flavia Pauri, Flavia Pauri, Paolo Maria Rossini, Paolo Maria Rossini, } "Near-infrared spectroscopy of the human brain: effects of apnea and hypercapnia on the intensity and phase of backscattered light", Proc. SPIE 3194, Photon Propagation in Tissues III, (1 January 1998); doi: 10.1117/12.301080; https://doi.org/10.1117/12.301080
PROCEEDINGS
8 PAGES


SHARE
Back to Top