14 January 1998 Comparative histologic study of alterations in rat skeletal muscles due to carbon dioxide laser with varying power but constant energy
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Abstract
The aim of our study was to compare biolgic effects such as tissue damage and regeneration in rat skeletal muscle after CO2 laser application with pulses of constant energy density, but with varying power and exposure time. We used three different laser conditions: 20 W by 0.5 s, 10 W by 1.0 s and 5.0 W by 2.0 s, all having the same energy density (10 joules in a constant area). The animals were sacrificed immediately after laser application, and after 1, 4, 7, 15 and 21 days. Tissue damage produced by the CO2 laser with high power provokes more profound craters with less tissue damage at the margins. As shown by lesser tissue carbonization, fewer foreign body giant cell granulomas and less tissue fibrosis and, on the other hand, an accelerated regeneration of muscle tissue.
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Ester Maria Danielli Nicola, Ester Maria Danielli Nicola, Adriana Azevedo Coutinho, Adriana Azevedo Coutinho, Konradin Metze, Konradin Metze, Jorge Humberto Nicola, Jorge Humberto Nicola, } "Comparative histologic study of alterations in rat skeletal muscles due to carbon dioxide laser with varying power but constant energy", Proc. SPIE 3195, Laser-Tissue Interaction, Tissue Optics, and Laser Welding III, (14 January 1998); doi: 10.1117/12.297890; https://doi.org/10.1117/12.297890
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