14 January 1998 Investigations of normal skin tissue using fiber optical FTIR spectroscopy
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Abstract
An innovative spectroscopic diagnostic method has been developed of investigation of different regions of normal human skin tissue. This new method is a combination of Fourier transform infrared fiberoptic evanescent wave (FTIR-FEW) spectroscopy and fiber optic technique for the middle infrared (MIR) wavelength range (3 to 20 micrometer). The fiberoptical sensors we have used are characterized by low optical losses and high flexibility for remote analysis. Our new fiber optical accessory can be utilized with a diversity of standard commercial Fourier transform spectrometers. FTIR-FEW, using nontoxic unclad fibers in the attenuated total reflection (ATR) regime, is suitable for noninvasive, fast, sensitive investigations of normal skin in vivo for various medical diagnostics applications including studies of acupuncture points. Our method allows for direct interaction of the skin tissue with the fiber. Here we present the first data on infrared spectra of skin tissue in vivo for several acupuncture points in the range of 1300 to 1800 cm-1 and 2600 to 4000 cm-1.
© (1998) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Angelique L. Brooks, Angelique L. Brooks, Reinhard F. Bruch, Reinhard F. Bruch, Natalia I. Afanasyeva, Natalia I. Afanasyeva, Sergei F. Kolyakov, Sergei F. Kolyakov, Leonid N. Butvina, Leonid N. Butvina, Lixing Ma, Lixing Ma, } "Investigations of normal skin tissue using fiber optical FTIR spectroscopy", Proc. SPIE 3195, Laser-Tissue Interaction, Tissue Optics, and Laser Welding III, (14 January 1998); doi: 10.1117/12.297892; https://doi.org/10.1117/12.297892
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