Automated classification of tissue by type using real-time spectroscopy

David A. Benaron M.D.; Wai-Fung Cheong; Joshua L. Duckworth; Kenneth Noles; Camran Nezhat; Daniel Seidman; Susan R. Hintz; Carl J. Levinson; Aileen L. Murphy; John W. Price Jr.; Frank W.H. Liu; David K. Stevenson; Eben L. Kermit

doi:10.1117/12.297957

29 December 1997 Automated classification of tissue by type using real-time spectroscopy

David A. Benaron M.D., Wai-Fung Cheong, Joshua L. Duckworth, Kenneth Noles, Camran Nezhat, Daniel Seidman, Susan R. Hintz, Carl J. Levinson, Aileen L. Murphy, John W. Price Jr., Frank W.H. Liu, David K. Stevenson, Eben L. Kermit

Author Affiliations +

Proceedings Volume 3197, Optical Biopsies and Microscopic Techniques II; (1997) https://doi.org/10.1117/12.297957
Event: BiOS Europe '97, 1997, San Remo, Italy

Abstract

Each tissue type has a unique spectral signature (e.g. liver looks distinct from bowel due to differences in both absorbance and in the way the tissue scatters light). While differentiation between normal tissues and tumors is not trivial, automated discrimination among normal tissue types (e.g. nerve, artery, vein, muscle) is feasible and clinically important, as many medical errors in medicine involve the misidentification of normal tissues. In this study, we have found that spectroscopic differentiation of tissues can be successfully applied to tissue samples (kidney and uterus) and model systems (fruit). Such optical techniques may usher in use of optical tissue diagnosis, leading to automated and portable diagnostic devices which can identify tissues, and guide use of medical instruments, such as during ablation or biopsy.

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David A. Benaron M.D., Wai-Fung Cheong, Joshua L. Duckworth, Kenneth Noles, Camran Nezhat, Daniel Seidman, Susan R. Hintz, Carl J. Levinson, Aileen L. Murphy, John W. Price Jr., Frank W.H. Liu, David K. Stevenson, and Eben L. Kermit "Automated classification of tissue by type using real-time spectroscopy", Proc. SPIE 3197, Optical Biopsies and Microscopic Techniques II, (29 December 1997); https://doi.org/10.1117/12.297957

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KEYWORDS

Tissues

Tissue optics

Absorbance

Biopsy

Kidney

Light sources

Medicine

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