Effect of laser-pulse structure and wavelength on wound healing

D. Scott Fortune; Shan Huang; G. Lee Bryant; C. Gaelyn Garrett M.D.; Lou Reinisch

doi:10.1117/12.312287

1 July 1998 Effect of laser-pulse structure and wavelength on wound healing

D. Scott Fortune, Shan Huang, G. Lee Bryant, C. Gaelyn Garrett M.D., Lou Reinisch

Proceedings Volume 3245, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VIII; (1998) https://doi.org/10.1117/12.312287
Event: BiOS '98 International Biomedical Optics Symposium, 1998, San Jose, CA, United States

Abstract

We have investigated wound healing of incisions in the buccal mucosa of a canine model created with the Vanderbilt Free Electron Laser tuned to 6.1, 6.45 and 6.8 microns. We have also used a carbon dioxide laser, continuous wave and with a short-pulse structure (100 microseconds) to access wavelength and pulse structure components to wound healing from laser incisions. The tissue was evaluated histologically and with tensiometry acutely and at post operative days 3, 7, and 14. The data indicate that shorter laser pulse durations create less lateral thermal injury and wounds with greater tensile strength, resulting in earlier wound healing. Wound healing was only slightly dependent upon the wavelength of the laser. These results demonstrate that surgical carbon dioxide lasers with a short-pulse structure of approximately 100 microseconds or less could offer more prompt wound healing while maintaining the advantages of a 10.6 micron wavelength laser.

Citation Download Citation

D. Scott Fortune, Shan Huang, G. Lee Bryant, C. Gaelyn Garrett M.D., and Lou Reinisch "Effect of laser-pulse structure and wavelength on wound healing", Proc. SPIE 3245, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VIII, (1 July 1998); https://doi.org/10.1117/12.312287

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