Tissue temperatures attained in indocyanine-green infiltrated and noninfiltrated bovine eyelids using diode laser (805-nm) energy at 3, 5, and 7 watts

John G. Kirkpatrick; Kenneth Eugene Bartels D.V.M.; D. Thomas Dickey; Ronald Powell; Steven A. Schafer; Jin Fu Zhou; James P. Wicksted

doi:10.1117/12.312315

1 July 1998 Tissue temperatures attained in indocyanine-green infiltrated and noninfiltrated bovine eyelids using diode laser (805-nm) energy at 3, 5, and 7 watts

John G. Kirkpatrick, Kenneth Eugene Bartels D.V.M., D. Thomas Dickey, Ronald Powell, Steven A. Schafer, Jin Fu Zhou, James P. Wicksted

Author Affiliations +

Proceedings Volume 3245, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VIII; (1998) https://doi.org/10.1117/12.312315
Event: BiOS '98 International Biomedical Optics Symposium, 1998, San Jose, CA, United States

Abstract

Normal non-pigmented bovine eyelids in two Hereford cows under general anesthesia were treated with diode laser (805 nm) in a power range of 3 - 6.5 watts. Tissue temperatures were measured in areas infiltrated with 0.25% indocyanine green (ICG) solution and in non-infiltrated areas. Targeted tissue was laser treated at post-injection time intervals of 1 to 60 minutes. Temperatures were measured with a computerized temperature sensing program using hypodermic needle thermistors. Trial objectives were to establish power/chromophore concentration/time parameters to create tumor and peri-tumor tissue temperatures of 50 degrees Celsius without causing epidermal vaporization. Tissue temperature of 50 degrees Celsius has been established as the temperature producing coagulative necrosis of squamous cell carcinoma tumor tissue in 30 seconds. This temperature was produced in chromophore-enhanced tissue bit without repeatable confidence. Bovine ocular squamous cell carcinoma (BOSCC)-affected eyes and eyelids have been successfully treated with carbon dioxide focused and defocused laser with and without chromophore enhanced diode laser (805 nm) energy. The need for tumor staging and procedure standardization requires further investigation to determine laser power/chromophore concentration, and issue exposure times.

Citation Download Citation

John G. Kirkpatrick, Kenneth Eugene Bartels D.V.M., D. Thomas Dickey, Ronald Powell, Steven A. Schafer, Jin Fu Zhou, and James P. Wicksted "Tissue temperatures attained in indocyanine-green infiltrated and noninfiltrated bovine eyelids using diode laser (805-nm) energy at 3, 5, and 7 watts", Proc. SPIE 3245, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VIII, (1 July 1998); https://doi.org/10.1117/12.312315

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
4 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Tissues

Laser tissue interaction

Semiconductor lasers

Temperature metrology

Tumors

Skin

Indocyanine green

Show All Keywords

Keywords/Phrases

Search In:

Publication Years