1 July 1998 Tissue temperatures attained in indocyanine-green infiltrated and noninfiltrated bovine eyelids using diode laser (805-nm) energy at 3, 5, and 7 watts
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Proceedings Volume 3245, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VIII; (1998) https://doi.org/10.1117/12.312315
Event: BiOS '98 International Biomedical Optics Symposium, 1998, San Jose, CA, United States
Abstract
Normal non-pigmented bovine eyelids in two Hereford cows under general anesthesia were treated with diode laser (805 nm) in a power range of 3 - 6.5 watts. Tissue temperatures were measured in areas infiltrated with 0.25% indocyanine green (ICG) solution and in non-infiltrated areas. Targeted tissue was laser treated at post-injection time intervals of 1 to 60 minutes. Temperatures were measured with a computerized temperature sensing program using hypodermic needle thermistors. Trial objectives were to establish power/chromophore concentration/time parameters to create tumor and peri-tumor tissue temperatures of 50 degrees Celsius without causing epidermal vaporization. Tissue temperature of 50 degrees Celsius has been established as the temperature producing coagulative necrosis of squamous cell carcinoma tumor tissue in 30 seconds. This temperature was produced in chromophore-enhanced tissue bit without repeatable confidence. Bovine ocular squamous cell carcinoma (BOSCC)-affected eyes and eyelids have been successfully treated with carbon dioxide focused and defocused laser with and without chromophore enhanced diode laser (805 nm) energy. The need for tumor staging and procedure standardization requires further investigation to determine laser power/chromophore concentration, and issue exposure times.
© (1998) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
John G. Kirkpatrick, John G. Kirkpatrick, Kenneth Eugene Bartels, Kenneth Eugene Bartels, D. Thomas Dickey, D. Thomas Dickey, Ronald Powell, Ronald Powell, Steven A. Schafer, Steven A. Schafer, Jin Fu Zhou, Jin Fu Zhou, James P. Wicksted, James P. Wicksted, } "Tissue temperatures attained in indocyanine-green infiltrated and noninfiltrated bovine eyelids using diode laser (805-nm) energy at 3, 5, and 7 watts", Proc. SPIE 3245, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VIII, (1 July 1998); doi: 10.1117/12.312315; https://doi.org/10.1117/12.312315
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