Contact fiber probes for in-vivo optical spectroscopy: comparative analysis

Nikolay A. Denisov; Stephen E. Griffin

doi:10.1117/12.305388

16 April 1998 Contact fiber probes for in-vivo optical spectroscopy: comparative analysis

Nikolay A. Denisov, Stephen E. Griffin

Proceedings Volume 3250, Optical Biopsy II; (1998) https://doi.org/10.1117/12.305388
Event: BiOS '98 International Biomedical Optics Symposium, 1998, San Jose, CA, United States

Abstract

In recent years, in-vivo optical spectroscopy has become widely used during many routine endoscopic procedures for purposes of biomedical science and practical medicine by virtue of its non-invasive effect and real time remote detection convenience. Fiber optic probes are an important unit of spectroscopic equipment for providing effective excitation and light gathering on site. Probes should be small enough to be easy introduced into the instrumentation channel of standard flexible or rigid endoscopes. Several commercial and custom types of fiber tips for applications in diagnostics have been examined. Single- and multifiber delivery schemes are also discussed. To provide comparative analyses of probes' optical properties, sensor optical efficiency and tip coupling efficiency coefficients have been proposed. These coefficients are a quantitative measure of probe optical efficiency and have been calculated by means of ray tracing for both fiber-tissue and tissue-fiber traces. These results could be a helpful tool for designers of fiber probes for Raman, laser-induced fluorescence and elastic-scattered spectroscopy of internal human organs.

Citation Download Citation

Nikolay A. Denisov and Stephen E. Griffin "Contact fiber probes for in-vivo optical spectroscopy: comparative analysis", Proc. SPIE 3250, Optical Biopsy II, (16 April 1998); https://doi.org/10.1117/12.305388

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