13 May 1998 Lipometer subcutaneous adipose tissue topography (SAT-Top) reflects serum leptin levels varying in circadian rhythms
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Proceedings Volume 3254, Laser-Tissue Interaction IX; (1998) https://doi.org/10.1117/12.308196
Event: BiOS '98 International Biomedical Optics Symposium, 1998, San Jose, CA, United States
Recent advances in obesity research have shown that the product of the ob-gene named leptin is related to total body fast mass in humans. There is, however, a debate if leptin levels are pulsatile and linked to body fat distribution. In this study we therefore investigated the subcutaneous adipose tissue topography (SAT-Top) measured by means of the newly developed device Lipometer and leptin levels during a 24 hours beginning at 0715am ending the same time in the next day. Blood samples for measurement of leptin were taken every 3 hours in a male subject. Measurements of SAT-Top were performed at 15 body sites from neck to calf at the left and right body site at the same time interval. We observed an almost symmetrically reaction of the left and right body site with a maximum of the mean value of all body sites in the evening at 0715pm. There was a negative correlation between serum leptin levels and SAT-Top using the set of certain body sites (R2 equals 0.80, p equals 0.01). If these combination of body sites is inversed and set against serum leptin levels, both curves show almost identical shape and time dependence. We conclude that SAT-Top by means of Lipometer is changed in a short time and related to leptin levels in the investigated male subject.
© (1998) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Reinhard Moeller, Reinhard Moeller, Erwin Tafeit, Erwin Tafeit, Karl Sudi, Karl Sudi, Karoline Vrecko, Karoline Vrecko, Renate Horejsi, Renate Horejsi, Helmut G. Hinghofer-Szalkay, Helmut G. Hinghofer-Szalkay, Gilbert Reibnegger, Gilbert Reibnegger, } "Lipometer subcutaneous adipose tissue topography (SAT-Top) reflects serum leptin levels varying in circadian rhythms", Proc. SPIE 3254, Laser-Tissue Interaction IX, (13 May 1998); doi: 10.1117/12.308196; https://doi.org/10.1117/12.308196

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