13 May 1998 Relief of vasospasm by intravascular ultraviolet irradiation
Author Affiliations +
Proceedings Volume 3254, Laser-Tissue Interaction IX; (1998) https://doi.org/10.1117/12.308205
Event: BiOS '98 International Biomedical Optics Symposium, 1998, San Jose, CA, United States
We investigated the photovasorelaxation with intravascular transluminal irradiation using in vivo model. A 2.5 Fr. catheter was inserted in the femoral artery of a rabbit under anesthesia. A 400 micrometers diameter quartz fiber was inserted through the catheter. The catheter was withdrawn from the distal end to the proximal end of the exposed femoral artery without laser irradiation in order to observe the mechanical dilation by the procedure. The femoral artery lumen was irradiated by a Helium-Cadmium(He-Cd) laser (wavelength; 325 nm) with 8 mW through the fiber during 30 s. We carried out that the laser irradiation produced vasorelaxation (185% on the average) compared with mechanical vasodilation (150% on the average) with angiography. The results suggest that intravascular transluminal irradiation with low-power UV laser might be applicable to the relief of acute arterial vasospasm.
© (1998) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Kanji Nakai, Kanji Nakai, Yuji Morimoto, Yuji Morimoto, Hirotaka Ito, Hirotaka Ito, Kimito Kominami, Kimito Kominami, Hirotaka Matsuo, Hirotaka Matsuo, Tsunenori Arai, Tsunenori Arai, Makoto Kikuchi, Makoto Kikuchi, } "Relief of vasospasm by intravascular ultraviolet irradiation", Proc. SPIE 3254, Laser-Tissue Interaction IX, (13 May 1998); doi: 10.1117/12.308205; https://doi.org/10.1117/12.308205

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