24 April 1998 Near-infrared muscle oximeter that can correct the influence of a subcutaneous fat layer
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Proceedings Volume 3257, Infrared Spectroscopy: New Tool in Medicine; (1998) https://doi.org/10.1117/12.306080
Event: BiOS '98 International Biomedical Optics Symposium, 1998, San Jose, CA, United States
Abstract
The inhomogeneity of tissue structure greatly affects the sensitivity of tissue oxygenation measurement by reflectance NIRS. We have proposed a method for correcting the influence of a subcutaneous fat layer on muscle oxygenation measurement. In this study, this method was validated by measuring the peak-to-peak variation of muscle oxygenation in periodic exercise tests on the vastus lateralis and the falling rate of oxygenation in ischemia tests on the forearm. A newly developed multisensor probe with source- detector distances of 7-40 mm was used. THe probe, consisting of a two-wavelength LED and four photodiodes, was connected to a 4-channel tissue oxygen monitor. The fat layer thickness was also measured by ultrasonography. Results of the tests clearly showed that the presence of a fat layer greatly decreases the sensitivity of measurement and increases the light intensity at a detector. The correction factors of sensitivity were determined from this relationship and Monte Carlo simulation. The corrected oxygenation levels were quantitatively compared among subjects in spite of different fat layer thicknesses.
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Katsuyuki Yamamoto, Masatsugu Niwayama, Ling Lin, Toshikazu Shiga, Nobuki Kudo, Makoto Takahashi, "Near-infrared muscle oximeter that can correct the influence of a subcutaneous fat layer", Proc. SPIE 3257, Infrared Spectroscopy: New Tool in Medicine, (24 April 1998); doi: 10.1117/12.306080; https://doi.org/10.1117/12.306080
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