Running a printing press requires frequent measurements in order to achieve and maintain an acceptable level of print quality. Ideally, on-line measurements should be made within an image and automatically used to adjust the inking system to achieve and maintain the desired target values. However, there are still several obstacles to this approach. As an intermediate solution, we have developed a system for quality control in newspaper printing, consisting of a mini-target, an optical device, and a three chip CCD camera. The measurements are made off-line. Individual prints are analyzed from which the behavior of the printing press can be studied. The mini- target was minimized to approximately 1/9 of a square inch, which is more than a magnitude smaller compared to control strips commonly used. The mini-target contains areas of solid tone, halftone and elements for register control. Due to its small dimensions it is accepted in newspaper printing. The CCD camera is a commercially available 3 chip 8-bit camera. Using the camera and image analysis software which has been developed, we are able to measure registration, solid-tone density, dot gain and colorimetric values. A measurement is performed by capturing the image of the test target in one shot followed by image analysis. The reproducibility of the system is high. Misregistration can be determined in the range of plus or minus 200 micrometers with an accuracy of about 20 micrometers.