Optimization of CO2 arteriography based on flow regime maps of co-current gas-liquid pulsatile flow

Albert A. Gossler; Elvira V. Lang; William Barnhart

doi:10.1117/12.312553

3 July 1998 Optimization of CO₂ arteriography based on flow regime maps of co-current gas-liquid pulsatile flow

Albert A. Gossler; Elvira V. Lang; William Barnhart

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Proceedings Volume 3337, Medical Imaging 1998: Physiology and Function from Multidimensional Images; (1998) https://doi.org/10.1117/12.312553
Event: Medical Imaging '98, 1998, San Diego, CA, United States

Abstract

The intravascular use of CO₂ as a contrast medium for diagnosis of vaso-occlusive disease has the potential of improved safety and reduced cost compared to conventional contrast solutions. Optimal imaging using any gaseous contrast medium is strongly dependent on the fluid mechanics of pulsatile gas-liquid flow. Gas-liquid flow regimes can be designated by the visually identifiable patterns of annular flow, stratified flow, intermittent flow, and dispersed bubble flow. This paper presents an analytically developed flow regime map for gas-liquid pulsatile flow and preliminary experimental results testing the flow regime map predictions. Preliminary experimental results confirm analytical predictions: (1) Use of CO₂ for intervascular vaso- occlusive imaging under typical conditions may result in a periodic intermittent flow; (2) Periodic intermittent flow is encountered at lower liquid and gas flow rates than is steady- state intermittent flow; (3) Reliable prediction of the flow regime in coordination with precise CO2 delivery can be used to prescribe a flow regime optimal for intravascular vaso- occlusive imaging.

Citation Download Citation

Albert A. Gossler, Albert A. Gossler, Elvira V. Lang, Elvira V. Lang, William Barnhart, William Barnhart, } "Optimization of CO₂ arteriography based on flow regime maps of co-current gas-liquid pulsatile flow", Proc. SPIE 3337, Medical Imaging 1998: Physiology and Function from Multidimensional Images, (3 July 1998); doi: 10.1117/12.312553; https://doi.org/10.1117/12.312553

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