25 March 1998 Multiple protein sequence comparison by genetic algorithms
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In the analysis of molecular evolution, it is very frequent to consider M sequences at a time, where M greater than 2. The simultaneous study of the relationships among M sequences is a large and difficult problem. This paper presents a new approach to multiple protein sequence comparison based on Genetic Algorithms, (G.A.). In particular, it is described an algorithm for finding the alignment of three protein sequences; besides, it can be easily changed for finding the alignment of more than three sequences or for other types of sequences. The G.A. was originally developed for only two sequences comparison [Morato96].
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Raquel Roche Gonzalez, Carmen Morato Izquierdo, Juan Seijas, "Multiple protein sequence comparison by genetic algorithms", Proc. SPIE 3390, Applications and Science of Computational Intelligence, (25 March 1998); doi: 10.1117/12.304857; https://doi.org/10.1117/12.304857


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