This paper is proposed by the laboratory of ISPESL involved, in particular, in the study of interactions between industrial plants and natural hazards. For the determining of eventual short term effects of a catastrophic and/or extreme natural event, a study site in the industrial area of Ascoli Piceno (Marche Region, Central Italy) has been individuated. This area is particularly interesting and sensitive due to the coexistence of industrial plants and urban settlements in a fluvial environment. The study of updated stereoscopic aerial photos, integrated by field survey and information for different sources, has allowed the definition of land vulnerability and the individuation of different natural hazards. As outlined by this analysis, the major geomorphologic risk, in the study area, is represented by the eventual flooding of River Tronto. Indeed many of the industrial plants are located in the flood area of the river, just a few meters above the mean river water level. For that concerns this kind of event a zoning of hazard has been derived from stereoscopic aerial photos analysis, integrated by hydrological, geological and geomorphological data.